SupplySide Stage – Immune health formulation alert: Clinical immune enhancement and cellular health activity from a natural anthocyanin-fucoidan nano complex (AFNC)

Immune health needs have pivoted post-pandemic. No longer are formulators looking to quell acute care needs — they are looking to create products that support healthy immune responses for daily care and maintain a strong, active immune system in balance.

AFNC has demonstrated significant immune-enhancing effects in clinical settings. In macrophages, AFNC increased the production of cytokines and nitric oxide, activated NF-κB signaling pathways and enhanced iNOS (inducible nitric oxide synthase) expression. In trials with cyclophosphamide-induced immunosuppressed mice, AFNC restored immune cytokine levels in the serum and spleen, suggesting its potential related to maintaining healthy immune function.