Quatrefolic® 5-MTHF as Glucosamine Salt

With Quatrefolic® Gnosis by Lesaffre has managed to develop an innovative product with significant advantages over previous folate generations while maintaining the same biological properties of 5-methyltetrahydrofolate. This remarkable step forward is attributed to the development of the glucosamine salt of Quatrefolic®, through two main steps: Improving solubility in water of 5-methyltetrahydrofolate, Quatrefolic® is defined as water soluble, a significant opportunity for improving bioavailability, whereas the calcium salt version is defined as sparingly soluble. Guaranteeing a safety and high-quality stable profile by choosing glucosamine as natural compound naturally present in the body. What is glucosamine salt made from? It is a natural compound endogenously formed throughout the human body by cellular glucose metabolism and found in almost all human tissues. Glucosamine is made up of glucose and amino acid glutamine and it is a key building block for several structures. In the body it is needed to produce glycosaminoglycans, molecules used in the formation and reparation of cartilage and other body tissues. Glucosamine has an extremely safe profile and it has been recognized as GRAS for its use as a nutritional supplement to promote joint health. It has been widely used as a human dietary supplement for years, both alone and in combination with other products. As a result of our clinical research, Quatrefolic® can claim key relevant benefits allowing the product to be suitable for dietary supplements as well as food and beverage uses, specifically for combinations of different vitamins and minerals. Quatrefolic® is manufactured under controlled conditions according to cGMP, and since the glucosamine is animal- and shellfish-free, Quatrefolic® is an excellent option for vegetarians.