polymers, the bioactive compounds shown to support healthy blood sugar, cardiovascular function, hormonal balance, and antioxidant protection.* Its proprietary 20:1 water-soluble extraction delivers a clean, concentrated ingredient ideal for metabolic and healthy aging formulations.
The active ingredient is Cinnamon bark extract (Cinnamomum cassia), which supports healthy fasting blood glucose levels and promotes optimal glucose utilization, supports healthy systolic blood pressure, and promotes endothelial function for smooth blood flow.* It has also been clinically shown to support menstrual cyclicity and healthy hormone balance in women, supports healthy body composition and metabolic features associated with prediabetic conditions, helps increase total antioxidant capacity and reduce oxidative lipid damage, and supports muscle recovery, reduced exercise-related fatigue, and performance resilience.*
Cinnulin PF® is backed by four randomized, double-blind, placebo-controlled human studies. At 500 mg per day over 12 weeks, it demonstrated support for healthy fasting blood glucose, systolic blood pressure, and lean mass. At 1,500 mg per day over 6 months, it showed a 79% average improvement in menstrual cyclicity among women with PCOS. Another 12-week study at 500 mg per day found increased antioxidant capacity and reduced oxidative lipid damage, while an 8-week study at 500 mg per day in athletes showed reduced muscle soreness, improved recovery, and lower fatigue markers.
Cinnulin PF® supports multiple pathways involved in glucose metabolism and cellular health, including insulin signaling pathways, protein tyrosine phosphatase activity, phosphatidylinositol 3-kinase activity, glucose transport mechanisms, endothelial cell function and glucose uptake, antioxidant properties, sirtuin activity, and stimulation of insulin receptor autophosphorylation.*
For applications in blood sugar management, women's health, cardiovascular health, and weight management.
