Motherwort Extract

Introduction to Motherwort Extract (Leonurus japonicus Houtt.)‌ Motherwort, scientifically known as Leonurus japonicus Houtt., is a perennial herbaceous plant belonging to the Lamiaceae family, widely distributed across China and other East Asian regions. Its dried aerial parts have been utilized for centuries in Traditional Chinese Medicine (TCM) under the name "Yimucao," primarily for gynecological and cardiovascular health support. The extract derived from this plant, known as Motherwort Extract, is a concentrated form of its bioactive compounds, offering standardized therapeutic benefits. Botanical Characteristics and Traditional Use‌ The plant features square stems, opposite leaves with serrated edges, and small purple flowers. Historically, Motherwort has been revered for its ability to invigorate blood circulation, dispel stasis, regulate menstruation, and promote postpartum recovery. In TCM, it is prescribed for conditions such as irregular menstruation, dysmenorrhea, postpartum blood stasis, and uterine contractions during labor. Its bitter and acrid taste, coupled with a cooling property, aligns with its role in addressing heat-related imbalances in the body. Chemical Composition‌ Motherwort Extract is rich in diverse bioactive compounds, including alkaloids (e.g., leonurine, stachydrine), diterpenes, flavonoids, phenolic acids, and volatile oils. These constituents contribute to its multifaceted pharmacological effects. Alkaloids like leonurine are particularly notable for their cardiovascular benefits, while flavonoids and phenolic acids exhibit antioxidant and anti-inflammatory properties. Pharmacological Properties‌ Uterine Stimulation‌: Motherwort Extract enhances uterine contractions, making it valuable in obstetrics for facilitating labor and promoting postpartum recovery by aiding in the expulsion of lochia (postpartum discharge). This effect is attributed to its ability to stimulate smooth muscle activity in the uterus.