
α-Cyclodextrin(α-CD)(CAS:10016-20-3)
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α‑Cyclodextrin (CAS 10016‑20‑3) is a cyclic oligosaccharide composed of six glucose units, possessing a hydrophobic cavity that forms stable inclusion complexes. In the food industry it serves mainly as a solubilizer, emulsifier and stabilizer, enhancing the water solubility of hydrophobic ingredients such as flavors, pigments and plant oils, masking off‑flavors and extending shelf life; as a soluble dietary fiber it helps regulate blood glucose and lipids, and is added to breads, biscuits, beverages, ready‑to‑eat cereals and other processed foods. In pharmaceuticals, alpha‑cyclodextrin is used as a drug carrier to markedly improve the solubility, stability and bioavailability of poorly soluble drugs, appearing in oral solid dosage forms and injectable formulations, facilitating sustained release or oral delivery of protein drugs such as insulin. In cosmetics, it acts as a molecular delivery medium, encapsulating active fragrances, vitamin C, antioxidants and other actives in creams, lotions, shampoos and toothpaste, preserving activity, reducing oxidative degradation and minimizing skin irritation, thereby enhancing moisturizing, anti‑aging and whitening effects. Its low toxicity, good water solubility and edibility have led to inclusion in food‑additive safety lists in many countries, confirming its safe use across food, pharmaceutical and cosmetic applications.
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