Mannitol(CAS:87-78-5)

Mannitol (CAS 87‑78‑5) is a low‑sweetness, low‑calorie polyol approved by the U.S. FDA and the EU as GRAS, and is widely used in food, pharmaceuticals, and cosmetics. In food, it serves as a low‑calorie sweetener and anti‑caking agent, added to candies, chewing gum, baked goods, and reduced‑sugar beverages to suppress crystallization, extend shelf life, and provide a cooling sensation. In pharmaceuticals, mannitol is a non‑sticky diluent and tablet excipient suitable for direct‑compression, wet granulation, and lyophilized formulations, masking bitterness and improving tablet hardness and disintegration; intravenously, its high‑osmolarity solution is employed to lower intracranial pressure, intra‑ocular pressure, and treat oliguria in acute renal failure, as well as to promote urinary excretion of toxins and metabolites. In cosmetics, its excellent humectancy, anti‑caking, and surfactant properties make it a moisturizer, thickener, emulsifier, and preservative in creams, cleansers, and sunscreens. Moreover, its low hygroscopicity and good film‑forming ability allow its use as a moisture‑proof coating for hard candies and dried fruits, enhancing appearance and storage stability.